Oxytetracycline Inj

Broad-spectrum tetracycline for respiratory infections, pinkeye, anaplasmosis, Potomac horse fever, and susceptible bacterial infections in horses and cattle. Broad-spectrum tetracycline antibiotic. Mechanism: reversibly binds 30S ribosomal subunit → blocks aminoacyl-tRNA attachment to mRNA-ribosome complex → bacteriostatic inhibition of protein synthesis. Active against gram-positive, gram-negative, Rickettsia, Anaplasma, Chlamydia, Mycoplasma. Chelates divalent cations — avoid concurrent dairy/antacids. IV form (flexor tendon contracture treatment in foals at low dose). Key information Chelated by calcium, antacids, dairy, iron — administer separately by 2+ hours. Do not use in neonates (bone/tooth effects). Food animal withdrawal times required.

IV (horses): dilute to ≤10 mg/mL in sterile saline; infuse slowly over 30–60 min — rapid infusion causes cardiovascular collapse. Do NOT give IM in horses (tissue necrosis). SQ (cattle): inject at recommended site and volume. Foal contracture treatment: dilute and infuse IV slowly over 60 min. Store at room temperature; protect from light. If a dose is missed Administer as soon as you remember. If it is almost time for the next scheduled dose, skip the missed dose and resume the normal schedule. Never double up doses to make up for a missed one. Always complete the full antibiotic course and separate from dairy/antacids.

IV: cardiovascular collapse/arrhythmias with rapid injection (must dilute and infuse slowly). GI: diarrhea, anorexia. Tooth and bone developmental effects in young animals. Photosensitivity. Hepato/nephrotoxicity (high doses). IM: severe tissue necrosis (200 mg/mL formulation in horses). Superinfection. Foals: IV infusion may cause collapse — use extreme caution.

For animals IV: must dilute and administer slowly — rapid infusion causes cardiovascular collapse in horses. IM: avoid in horses (severe tissue necrosis — use IV route). Foals: low-dose IV used for contracted flexor tendons — monitor for diarrhea and nephrotoxicity. Use with caution in pregnant animals. Avoid concurrent dairy, antacids, or multivalent cations. Observe food animal withdrawal times for milk and meat. For people handling this medication Wear gloves when handling. Wash hands thoroughly with soap and water after handling. Tetracycline — Keep out of reach of children. Pregnant women and women of childbearing age should avoid contact. Affects fetal bone/teeth. Photosensitivity. Tissue necrosis risk with accidental injection (high concentration formulations).

Contact your veterinarian. Overdose causes GI signs, liver toxicity, and kidney damage at very high doses.