Oxytocin 100ml 20usp Units/ml Injectable

Uterine contractility stimulant for expulsion of retained placenta in mares; milk let-down stimulation; induction/augmentation of parturition. Endogenous octapeptide uterotonic/galactagogue hormone. Mechanism: binds oxytocin receptors (OTR) on uterine smooth muscle → G-protein signaling → increased intracellular calcium → uterine contraction. Myometrial sensitivity increases near parturition with rising estrogen. Also stimulates myoepithelial cell contraction → milk ejection. Short half-life (3–5 min); repeated dosing required. Key information Refrigerate. IV or IM administration. Use with veterinary supervision — may cause tetanic uterine contractions. Ensure complete cervical dilation before use in dystocia. Cardiac effects at high doses.

IM injection: administer deep IM into large muscle mass. IV (parturition induction/post-partum — only by veterinarian): dilute and administer as slow IV or CRI. Ensure cervix is dilated and obstruction is ruled out before use. Intranasal drops (milk letdown): instill into nostril 2–5 min before nursing. Store at room temperature; protect from light. If a dose is missed This medication is administered by a veterinarian or veterinary staff in a clinical setting. Missed doses are managed by your veterinary team — contact your veterinarian to reschedule.

Uterine tetany/rupture with excessive doses or inappropriate timing. Fetal distress/fetal death (if cervix not dilated). Cardiovascular: hypotension, tachycardia. Retained placenta fragments after forced delivery. Water intoxication (ADH-like antidiuretic effect with high doses). Milk letdown only (physiological — low doses).

For animals CONTRAINDICATED if cervix is not dilated or if obstruction is present — uterine rupture risk. Avoid in fetal malpresentation. Do not use in cases of fetal oversize. Limit repeat dosing (tachyphylaxis). Monitor fetal heart rate during administration. Observe food animal withdrawal times for milk and meat. For people handling this medication Wear gloves when handling. Wash hands thoroughly with soap and water after handling. Uterotonic hormone — Keep out of reach of children. Pregnant women and women of childbearing age should avoid contact. Can induce uterine contractions in pregnant women with skin/injection exposure. Wear gloves. If accidentally self-injected, seek medical attention.

Contact your veterinarian. Oxytocin overdose causes sustained uterine contractions, fetal distress, and cardiovascular effects. Administered by veterinary staff.