Panacur

Fenbendazole 10% (100mg/ml)

General Drug Information and Indications

Fenbendazole broad-spectrum anthelmintic for internal parasites (strongyles, roundworms, tapeworms, bots) in horses; also dogs, cats, and cattle. Benzimidazole anthelmintic (fenbendazole). Mechanism: binds beta-tubulin → inhibits tubulin polymerization and microtubule assembly → collapses parasite cytoskeleton → impaired glucose uptake and cellular division → death of susceptible nematodes. Larvicidal at high doses (larval cyathostomiasis). Good safety margin. Oral paste or granules. Key information Fenbendazole anthelmintic. Store at room temperature. Shake suspension well. Safe in pregnancy. Administer with food. Extended 5-day protocol for Giardia and some resistant parasites.

How to Give this Medication

Oral paste (horses): administer via dose syringe into the back of the mouth at the correct body weight marking. Ensure complete delivery by checking syringe after dosing. Oral granules: mix into a small portion of grain. Oral suspension (small animals): administer orally or mix into food. Administer with food to reduce GI adverse effects. Store at room temperature; protect from light. If a dose is missed Give the missed dose as soon as you remember and continue the course. Fenbendazole is often given daily for 3–5 days.

Side Effects

Generally very well tolerated. GI: transient soft feces, mild diarrhea (uncommon, usually self-limiting). Rare hypersensitivity to dying parasites (larval migration). Very wide safety margin.

Precautions

For animals Resistance monitoring recommended (fecal egg count reduction test). High-dose protocol (5 days) for larval cyathostomiasis — monitor for colic during die-off. Dose by body weight accurately. Use with caution in pregnant animals. at standard doses (appears safe); high doses — avoid in first trimester. Not approved for use in food-producing animals. at extra-label doses. For people handling this medication Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children. If accidental ingestion occurs, contact Poison Control (1-800-222-1222). Benzimidazole anthelmintic — Wash hands thoroughly with soap and water after handling. after handling. Keep out of reach of children. Pregnant women and women of childbearing age should avoid contact. Potential teratogen — avoid in pregnancy.

Overdose

Contact your veterinarian. Fenbendazole is very safe with a wide margin — mild GI signs are most likely. Contact your veterinarian, a veterinary emergency clinic, or the ASPCA Animal Poison Control Center (888-426-4435) immediately. Do not induce vomiting unless specifically directed by a veterinary professional.

Panacur dosage forms

ProductStrengthFormSizeType
PANACUR 1000ML 100 MG/ML SUSPENSION100 MG/MLSuspension1Commercial
PANACUR 25 GRAM PASTE 10% PASTE: FENBENDAZOLE—Paste1Commercial
PANACUR GALLON SUSPENSION 10% ORAL SUSP: FENBENDAZOLE—Suspension1Commercial
PANACUR POWERPAC———Commercial

Sources

This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual – Anthelmintics in Animals; Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)