Pantoprazole Inj
Call to order(859) 281-9511General Drug Information and Indications
Proton pump inhibitor (PPI) for GI ulcers and hypersecretory conditions; IV form for horses and small animals unable to take oral medications.
Proton pump inhibitor (PPI) injectable (pantoprazole sodium). Mechanism: benzimidazole prodrug activated by acid → covalently binds H+/K+-ATPase → irreversible proton pump inhibition → sustained gastric acid suppression. IV formulation useful when oral omeprazole not feasible. Onset faster than oral PPIs.
Key information
IV PPI — gastric acid suppression. Reconstitute with NS only. Stable 6 hours after reconstitution. Filter with in-line 1.2 micron filter. Compatible with limited IV solutions.
How to Give this Medication
IV: dilute reconstituted solution in 100 mL 0.9% NaCl; infuse over 15 min via IV catheter. Administer once or twice daily. Do not administer as rapid IV push. Store at room temperature; protect from light. (reconstituted — use within 6 hrs); Store refrigerated (2–8°C); do not freeze. (unreconstituted).
If a dose is missed
This medication is administered by a veterinarian or veterinary staff in a clinical setting. Missed doses are managed by your veterinary team — contact your veterinarian to reschedule.
Side Effects
Generally well tolerated. GI: diarrhea, nausea, abdominal pain. Hypomagnesemia (prolonged IV use). Drug interactions: reduced absorption of pH-dependent drugs. Thrombophlebitis (IV). Headache (IV infusion).
Precautions
For animals
IV PPI — monitor for hypomagnesemia with prolonged use. Drug interactions: same as oral PPI (reduces pH-dependent drug absorption). Reduce dose or extend interval in renal impairment. Use with caution in hepatic impairment.
For people handling this medication
Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children. If accidental ingestion occurs, contact Poison Control (1-800-222-1222). PPI — Wash hands thoroughly with soap and water after handling. after handling. Keep out of reach of children.
Overdose
Contact your veterinarian. IV PPI overdose causes GI signs. Rarely serious.
Pantoprazole Inj dosage forms
| Product | Strength | Form | Size | Type |
|---|---|---|---|---|
| PANTOPRAZOLE INJ 40 MG IV | 40 MG | Injectable | 1 | Commercial |
Sources
This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual – Drugs Used to Treat Gastrointestinal Ulcers in Monogastric Animals (https://www.merckvetmanual.com/pharmacology/systemic-pharmacotherapeutics-of-the-digestive-system/drugs-used-to-treat-gastrointestinal-ulcers-in-monogastric-animals); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)