General Drug Information and Indications

Penicillin V potassium oral tablets for susceptible gram-positive bacterial infections including streptococcal and staphylococcal infections in dogs and cats. Penicillin V potassium oral tablets. Mechanism: penicillinase-sensitive beta-lactam — binds PBPs → inhibits cell wall synthesis (bactericidal). Acid-stable oral formulation. Narrower gram-negative spectrum than ampicillin. For susceptible gram-positive infections in dogs and cats. Key information Penicillin V potassium — oral penicillin. Administer on empty stomach. Do not use in rabbits or hindgut fermenters. Store at room temperature.

How to Give this Medication

Oral tablets: Administer orally. May be given with food to improve compliance and reduce GI upset. Administer on an empty stomach for optimal absorption. for best absorption. Complete full course. Store at room temperature; protect from light. If a dose is missed Administer as soon as you remember. If it is almost time for the next scheduled dose, skip the missed dose and resume the normal schedule. Never double up doses to make up for a missed one. Complete the full antibiotic course.

Side Effects

Hypersensitivity reactions (urticaria, pruritus, anaphylaxis). GI: vomiting, diarrhea (oral). Superinfection. Small herbivores: fatal enterocolitis — contraindicated.

Precautions

For animals Oral penicillin V — avoid in small herbivores (fatal enterocolitis). Reduce dose or extend interval in renal impairment. For people handling this medication Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children. If accidental ingestion occurs, contact Poison Control (1-800-222-1222). Penicillin-class — inform doctor if penicillin-allergic. Wash hands thoroughly with soap and water after handling.

Overdose

Contact your veterinarian. Oral penicillin V overdose typically causes GI signs. Serious toxicity is rare.

Penicilln Vk Tab dosage forms

ProductStrengthFormSizeType
PENICILLN VK TAB 250MG (HIKMA)250 MGTablet1Commercial
PENICILLN VK TAB 500MG500 MGTablet1Commercial
PENICILLN VK TAB 500MG (RISING)500 MGTablet1Commercial

Sources

This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual – Penicillins Use in Animals (https://www.merckvetmanual.com/pharmacology/antibacterial-agents/use-of-penicillins-in-animals); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)