Pilocarpine Sol

Cholinergic miotic for glaucoma and keratoconjunctivitis sicca; increases aqueous humor outflow; pupil constriction. Cholinomimetic miotic (pilocarpine HCl). Mechanism: direct muscarinic M3 receptor agonist in iris sphincter muscle → pupillary constriction (miosis); M3 stimulation in ciliary muscle → trabecular meshwork stretch → increased aqueous humor outflow → reduced IOP (glaucoma). Parasympathomimetic action. Key information Cholinergic miotic — ophthalmic for glaucoma. For ophthalmic use only. May cause miosis and brow ache. Refrigerate after opening.

Ophthalmic solution: Instill into the conjunctival sac; avoid touching dropper tip to eye or periocular tissue. Instill 1 drop into affected eye(s) q6–8h for glaucoma. Administer at consistent times. Store at room temperature; protect from light. If a dose is missed Apply the missed dose as soon as you remember. If it is almost time for the next application, skip it and resume the normal schedule. Do not apply extra product to compensate.

Ophthalmic: miosis, brow ache, headache, retinal detachment (rare — in predisposed patients). Accommodation spasm/myopia. Retinal tears (with prolonged use). Systemic (if absorbed): bradycardia, bronchospasm, salivation, GI cramping.

For animals Contraindicated as a glaucoma medication in patients with lens luxation (miosis worsens anterior lens luxation). Avoid in uveitic eyes. May cause retinal tears in predisposed patients (systemic administration). For people handling this medication Wash hands thoroughly with soap and water after handling. Cholinergic ophthalmic — if eye contact occurs, may cause excessive tearing, constricted pupil, blurred vision. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children.

Contact your veterinarian. Excessive pilocarpine can cause cholinergic signs: excessive salivation, GI cramping, and bradycardia. Contact your veterinarian or a veterinary emergency clinic immediately if you believe your animal has received an overdose. Bring the medication label and note the approximate amount given.