Piperazine & Fenbendazole Oral Suspension

Anthelmintic for intestinal nematodes (roundworms, ascarids) in horses, dogs, and cats; combined with pyrantel or fenbendazole. Anthelmintic piperazine compound (piperazine salts). Mechanism: GABA receptor agonist → hyperpolarization of nematode muscle membrane → flaccid paralysis of ascarid roundworms. Worms expelled by gut motility. Active primarily against Parascaris equorum and Toxocara; less effective against strongyles. Generally replaced by more broad-spectrum agents. Key information Anthelmintic. Store at room temperature. Administer per label. Not effective against all parasites — confirm target species.

Oral: mix powder or liquid into water or feed. Administer as a single oral dose at appropriate body weight. Administer with food to reduce GI adverse effects. for horses. Ensure complete consumption before restoring full feed access. Store at room temperature; protect from light. If a dose is missed Administer as soon as you remember. If it is almost time for the next scheduled dose, skip the missed dose and resume the normal schedule. Never double up doses to make up for a missed one.

GI: vomiting, diarrhea, abdominal cramping (at high doses). CNS: ataxia, tremors, seizures (overdose). Urticaria (hypersensitivity). Generally well tolerated at standard doses. Not effective against encysted cyathostomes.

For animals Limited spectrum — not effective against encysted small strongyles or encysted larvae. Avoid concurrent piperazine with chlorpromazine (additive tremors). Use with caution in pregnant animals. For people handling this medication Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children. If accidental ingestion occurs, contact Poison Control (1-800-222-1222). Anthelmintic — Wash hands thoroughly with soap and water after handling. after handling. Keep out of reach of children.

Contact your veterinarian. Piperazine overdose causes neurological signs (ataxia, tremors) in cats and dogs. GI signs in all species.