General Drug Information and Indications

Flunixin meglumine (NSAID) paste formulation for treatment of visceral pain (colic), musculoskeletal inflammation, and fever in horses. Flunixin meglumine oral paste (1.87%). Mechanism: non-selective COX inhibitor → reduces prostaglandin and thromboxane synthesis → anti-inflammatory, analgesic, and antipyretic effects. Aminonicotinic acid derivative. FDA-approved equine oral paste formulation. Key information Equine probiotic/supplement product. Store per label. Administer as directed. Safe for regular use.

How to Give this Medication

Oral paste (horses): administer via dose syringe into the back of the mouth. Once or twice daily as directed. Store at room temperature; protect from light. If a dose is missed Contact your veterinarian before giving an additional dose if one was missed.

Side Effects

GI: gastric and right dorsal colonic ulceration (horses). Renal: azotemia with dehydration. Tissue necrosis with perivascular injection. Do not combine with other NSAIDs or corticosteroids. See flunixin meglumine.

Precautions

For animals Horses: IV only (not IM). Monitor for GI ulceration; use with caution in animals with GI disease. Monitor renal function, hydration status, and urine output. Do not use concurrently with other NSAIDs or corticosteroids. Not approved for use in food-producing animals. For people handling this medication Wear gloves when handling. Wash hands thoroughly with soap and water after handling. Flunixin paste — NSAID. Wear gloves. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children.

Overdose

Contact your veterinarian or emergency clinic immediately. NSAID overdose causes GI ulceration and kidney damage.

Prevail dosage forms

ProductStrengthFormSizeType
PREVAIL 1500MG/30GM PASTE: FLUNIXIN MEGLUMINE30 GMPaste1Commercial
PREVAIL 50 MG/ML INJECTABLE: FLUNIXIN MEGLUMINE50 MG/MLInjectable—Commercial
PREVAIL 50 MG/ML INJECTABLE: FLUNIXIN MEGLUMINE50 MG/MLInjectable—Commercial

Sources

This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual – Nonsteroidal Anti-inflammatory Drugs in Animals (https://www.merckvetmanual.com/pharmacology/inflammation/nonsteroidal-anti-inflammatory-drugs-in-animals); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)