General Drug Information and Indications

Probiotic (Lactobacillus/Enterococcus) for restoration of GI microflora in horses and cattle during/after antibiotic therapy and GI disease. Multi-strain probiotic (Lactobacillus acidophilus, Streptococcus faecium, Lactobacillus casei, Bifidobacterium thermophilum). Mechanism: direct-fed microbials competitively exclude pathogenic bacteria from intestinal mucosa by competing for adhesion sites and nutrients; produce antimicrobial substances; stimulate local intestinal immune response. Live microorganisms. Key information Probiotic paste — Lactobacillus spp. Store at room temperature or refrigerate. Safe for all life stages. Administer directly or mix with feed.

How to Give this Medication

Oral paste or powder: Administer orally via dose syringe placed at the back of the tongue, or mix into a small amount of palatable feed. (paste) via dose syringe or mix powder into a small amount of palatable feed. Administer orally. May be given with food to improve compliance and reduce GI upset. Administer 2 hrs apart from antibiotics. Store at room temperature; protect from light. If a dose is missed Give the missed dose as soon as you remember. If you forget a day, simply resume the normal schedule the next day. Missing an occasional dose of this supplement is unlikely to cause harm.

Side Effects

GI: mild flatulence, loose feces (rare; as beneficial microflora reestablish). Generally very safe — no significant adverse effects. Mild GI adjustment period when starting.

Precautions

For animals Administer at least 2 hrs apart from antibiotics to prevent direct inactivation of live organisms. For people handling this medication Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children. If accidental ingestion occurs, contact Poison Control (1-800-222-1222). Probiotic — generally safe. Wash hands thoroughly with soap and water after handling.

Overdose

Overdose with this supplement is unlikely to cause serious harm at slightly elevated doses, but contact your veterinarian if a large excess was given or if your animal shows any unusual signs.

Probios Paste dosage forms

ProductStrengthFormSizeType
PROBIOS PASTE—Paste1Commercial

Sources

This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual (merckvetmanual.com); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)