Proparacaine Sol

General Drug Information and Indications

Topical ophthalmic local anesthetic for corneal anesthesia during ophthalmic examination and minor procedures. Ester-type local anesthetic (proparacaine HCl 0.5%). Mechanism: reversibly blocks sodium channels in corneal and conjunctival epithelium → prevents pain signal transmission. Ophthalmic topical only — rapid onset (20–30 sec), duration 10–20 min. Repeated use inhibits corneal epithelial healing — use only for examination/diagnosis, not pain management. Key information Topical ophthalmic anesthetic. For diagnostic use only. Do NOT send patient home with topical anesthetic — impairs corneal healing and protective reflexes. Refrigerate; stable 6 months after opening.

How to Give this Medication

Ophthalmic solution: Instill into the conjunctival sac; avoid touching dropper tip to eye or periocular tissue. — 1–2 drops; onset within 20–30 sec. For diagnostic procedures only — do not dispense for repeated owner use. Store refrigerated (2–8°C); do not freeze. If a dose is missed This medication is administered by a veterinarian or veterinary staff in a clinical setting. Missed doses are managed by your veterinary team — contact your veterinarian to reschedule.

Side Effects

Corneal epithelial toxicity and delayed healing with repeated use (use only for examination — not pain management). Transient stinging upon instillation (paradoxical). Periocular dermatitis. Systemic effects minimal.

Precautions

For animals DIAGNOSTIC USE ONLY — do not dispense for owner application for pain management (delays recognition of painful conditions; impairs healing). Inhibits corneal wound healing with repeated use. For people handling this medication Wash hands thoroughly with soap and water after handling. Ophthalmic local anesthetic — avoid human eye contact; causes corneal anesthesia. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children.

Overdose

Ophthalmic local anesthetic administered by veterinary staff. Contact your veterinarian if excessive product was used or if eye irritation persists.

Proparacaine Sol dosage forms

ProductStrengthFormSizeType
PROPARACAINE OPH SOL 0.5% 15ML——1Commercial

Sources

This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual (merckvetmanual.com); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)