Rebalance Oral Suspension 946 Ml
General Drug Information and Indications
Oral trimethoprim-sulfamethoxazole (TMS) suspension for susceptible bacterial infections in dogs and cats.
Oral trimethoprim-sulfamethoxazole (TMS) suspension for small animals. Mechanism: trimethoprim inhibits dihydrofolate reductase; sulfamethoxazole inhibits dihydropteroate synthase → sequential dual blockade of bacterial folate synthesis → synergistic bactericidal/bacteriostatic effect. 1:5 trimethoprim:sulfonamide ratio.
Key information
Trimethoprim/sulfamethoxazole oral suspension — see SMZ-TMP entry. Shake well. Ensure adequate water intake. Loading dose recommended.
How to Give this Medication
Oral suspension (dogs, cats): Shake well before each use. well. Administer orally. May be given with food to improve compliance and reduce GI upset. Administer with food to reduce GI adverse effects. Measure accurately. Store refrigerated (2–8°C); do not freeze.
If a dose is missed
Administer as soon as you remember. If it is almost time for the next scheduled dose, skip the missed dose and resume the normal schedule. Never double up doses to make up for a missed one. Shake well. Ensure adequate water intake. Complete the full course.
Side Effects
GI: vomiting, diarrhea, anorexia. Renal: crystalluria (ensure hydration). Hematologic: bone marrow suppression with prolonged use (CBC monitoring). KCS in dogs (chronic use). Sulfonamide hypersensitivity (fever, skin rash). Folate depletion.
Precautions
For animals
Ensure adequate hydration (crystalluria prevention). Reduce dose or extend interval in renal impairment. Monitor CBC periodically with prolonged use. Dogs: monitor for KCS with prolonged use. Inform doctor if sulfonamide-allergic.
For people handling this medication
Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children. If accidental ingestion occurs, contact Poison Control (1-800-222-1222). Potentiated sulfonamide — Wash hands thoroughly with soap and water after handling. after handling. Inform doctor if sulfa-allergic. Keep out of reach of children. Pregnant women and women of childbearing age should avoid contact.
Overdose
Contact your veterinarian. TMS suspension overdose causes GI signs. Ensure water intake.
Rebalance Oral Suspension 946 Ml dosage forms
| Product | Strength | Form | Size | Type |
|---|---|---|---|---|
| REBALANCE ORAL SUSPENSION 946 ML | — | Oral Suspension | 1 | Commercial |
Sources
This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual (merckvetmanual.com); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)