General Drug Information and Indications

Florfenicol + flunixin meglumine combination for bovine respiratory disease; antibiotic plus NSAID dual therapy. Combination antibiotic/NSAID injectable (florfenicol + flunixin meglumine). Florfenicol: amphenicol antibiotic binding 50S ribosome → bacteriostatic protein synthesis inhibition (active against Pasteurella, Mannheimia, Histophilus); flunixin meglumine: non-selective COX inhibitor → reduces fever, inflammation, and pain. Single-injection bovine respiratory disease treatment. Key information Florfenicol/flunixin meglumine combination. Beef withdrawal: 28 days (SQ). Do not use in veal calves. Injection site reactions common. IM or SQ only.

How to Give this Medication

SQ injection (cattle): inject SQ in the neck; maximum 10 mL per injection site. Shake well before each use. before use. Single dose. Store at room temperature; protect from light. If a dose is missed This medication is administered by a veterinarian or veterinary staff in a clinical setting. Missed doses are managed by your veterinary team — contact your veterinarian to reschedule.

Side Effects

Injection site reactions (florfenicol component — pain, swelling). Flunixin: GI ulceration, renal effects (dehydrated patients). Cardiovascular effects (flunixin IV). Tissue necrosis with perivascular injection (flunixin). Withdrawal times required.

Precautions

For animals Observe food animal withdrawal times for milk and meat. See florfenicol and flunixin precautions. Not for IV administration. Ensure adequate hydration. For people handling this medication Wear gloves when handling. Wash hands thoroughly with soap and water after handling. Combination antibiotic/NSAID injectable — wear gloves. Florfenicol: Keep out of reach of children. Pregnant women and women of childbearing age should avoid contact. Flunixin: avoid accidental injection. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention.

Overdose

Contact your veterinarian. Contains florfenicol and flunixin — overdose causes GI and NSAID-related effects.

Resflor (250 Ml) dosage forms

ProductStrengthFormSizeType
RESFLOR (250 ML) 300MG/16.5MG/ML INJECTABLE: FLORFENICOL AND FLUNIXIN MEGLUMIN16.5 MG/MLInjectable1Commercial

Sources

This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual (merckvetmanual.com); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)