Simparica Trio 5.6-11 Lb Chewable Tab

Combination ectoparasiticide/anthelmintic (sarolaner/moxidectin/pyrantel) for flea, tick, heartworm, and intestinal parasite control in dogs. Triple-combination monthly oral tablet (sarolaner + moxidectin + pyrantel). Sarolaner: isoxazoline — GABA/GluCl channel antagonist → ectoparasiticide (fleas, ticks); moxidectin: macrocyclic lactone → GluCl channel potentiation → heartworm and nematode prevention; pyrantel: nAChR agonist → intestinal nematode killing. Comprehensive parasiticide. Key information Sarolaner/moxidectin/pyrantel — combination parasite prevention. Dogs only. Monthly chewable. Use caution in dogs with neurological history (isoxazoline component). Administer with food.

Oral chewable tablet: Administer orally. May be given with food to improve compliance and reduce GI upset. Administer with food to reduce GI adverse effects. Administer monthly. Use correct weight-band product. Store at room temperature; protect from light. If a dose is missed Give the missed dose as soon as you remember and resume monthly administration.

GI: vomiting, diarrhea, anorexia, hypersalivation. CNS: tremors, ataxia, seizures (rare isoxazoline class effect — use with caution in dogs with seizure history). Generally well tolerated at labeled doses.

For animals Use with caution in dogs with seizure history. Not for puppies <8 weeks. Not approved for use in food-producing animals. For people handling this medication Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children. If accidental ingestion occurs, contact Poison Control (1-800-222-1222). Combination antiparasitic — Wash hands thoroughly with soap and water after handling. after handling. Keep out of reach of children.

Contact your veterinarian. Simparica Trio overdose may cause vomiting, muscle tremors, and neurological signs. Contact your veterinarian, a veterinary emergency clinic, or the ASPCA Animal Poison Control Center (888-426-4435) immediately. Do not induce vomiting unless specifically directed by a veterinary professional.