Soidum Bicarbonate

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General Drug Information and Indications

Sodium bicarbonate alkalinizing agent for treatment of metabolic acidosis; oral supplementation in horses with tying-up; buffering agent. Sodium bicarbonate (alkalinizing agent). Mechanism: bicarbonate directly neutralizes H+ ions → corrects metabolic acidosis; alkalinizes urine; shifts potassium intracellularly (treats hyperkalemia). Buffering agent in compounded formulations. Key information Sodium bicarbonate — see above entry.

How to Give this Medication

IV: dilute in compatible fluid; Administer IV slowly; rapid infusion may cause adverse reactions. Do not mix with calcium solutions. Store at room temperature; protect from light. If a dose is missed This medication is administered by a veterinarian or veterinary staff in a clinical setting. Missed doses are managed by your veterinary team — contact your veterinarian to reschedule.

Side Effects

Metabolic alkalosis (overdose). Hyponatremia or hypernatremia (volume and concentration dependent). Hypokalemia (alkalosis shifts K+ intracellularly). Gas production: bloating/colic if given with acidic drugs. Precipitation with calcium-containing fluids. Tetany (ionized calcium reduction in alkalosis).

Precautions

For animals Avoid in patients with metabolic alkalosis. Monitor pH, electrolytes, and calcium (ionized calcium decreases with alkalosis). Do not mix with calcium-containing solutions. Monitor volume status. For people handling this medication Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children. If accidental ingestion occurs, contact Poison Control (1-800-222-1222). Alkalinizing agent — generally safe. Wash hands thoroughly with soap and water after handling. IV form: administered by veterinary staff.

Overdose

Contact your veterinarian. Sodium bicarbonate overdose causes metabolic alkalosis. Managed by veterinary staff.

Soidum Bicarbonate dosage forms

ProductStrengthFormSizeType
SOIDUM BICARBONATE 5% INJECTABLE—Injectable1Commercial

Sources

This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual (merckvetmanual.com); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)