General Drug Information and Indications

Spectinomycin for susceptible gram-negative and mycoplasma infections in cattle and poultry. Aminocyclitol antibiotic (spectinomycin HCl). Mechanism: binds 30S ribosomal subunit (16S rRNA) in a non-overlapping site from aminoglycosides → inhibits bacterial protein synthesis (bacteriostatic; not bactericidal). Active against Mycoplasma, gram-negative organisms, some gram-positives. Injectable or oral administration. Key information Spectinomycin injectable antibiotic. For poultry/cattle. Withdrawal times required. Refrigerate.

How to Give this Medication

IM or oral as directed. Injectable: administer deep IM. Oral: Administer orally. May be given with food to improve compliance and reduce GI upset. Administer with food to reduce GI adverse effects. Store at room temperature; protect from light. If a dose is missed This medication is administered by a veterinarian or veterinary staff in a clinical setting. Missed doses are managed by your veterinary team — contact your veterinarian to reschedule.

Side Effects

GI: nausea, vomiting, diarrhea. Injection site reactions (IM). Generally well tolerated. Superinfection. Ototoxicity (high doses — aminocyclitol class, lower risk than aminoglycosides).

Precautions

For animals Avoid in patients with pre-existing renal impairment. Monitor renal function, hydration status, and urine output. Not approved for use in food-producing animals. For people handling this medication Wear gloves when handling. Wash hands thoroughly with soap and water after handling. Aminocyclitol antibiotic — Injectable — administered by veterinary staff only. Wash hands thoroughly with soap and water after handling. If accidentally self-injected, seek emergency medical attention immediately. Wear gloves.

Overdose

Contact your veterinarian. Spectinomycin overdose causes GI signs and possible injection-site reactions.

Speclinx-50 dosage forms

ProductStrengthFormSizeType
SPECLINX-50 16.7GM/33.3GM POWDER: LINCOMYCIN-SPECTINOMYCIN33.3 GMPowder1Commercial

Sources

This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual (merckvetmanual.com); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)