General Drug Information and Indications
Saturated potassium iodide for sporotrichosis, cutaneous pythiosis, and iodine deficiency states.
Saturated solution of potassium iodide (SSKI). Mechanism: high concentration iodide directly toxic to certain fungal organisms (Sporothrix, Pythium) via unknown mechanism possibly involving iodine generation; expectorant effect via gastric reflex stimulation of respiratory secretion; anti-inflammatory via reduction of thyroid hormone production (large doses).
Key information
Saturated solution of potassium iodide. Dilute in water before administration. Monitor for iodism. Used for sporotrichosis and lung conditions. Store at room temperature.
How to Give this Medication
Oral: dilute in water or juice to reduce GI irritation. Mix into grain for horses. Administer with food. Store at room temperature; protect from light. Protect from light.
If a dose is missed
Administer as soon as you remember. If it is almost time for the next scheduled dose, skip the missed dose and resume the normal schedule. Never double up doses to make up for a missed one.
Side Effects
GI: vomiting, anorexia, diarrhea (common with chronic use). Iodism: salivation, lacrimation, rhinorrhea, skin eruptions. Thyroid dysfunction. Cats: more sensitive — anorexia, hypothermia, skin lesions.
Precautions
For animals
See potassium iodide. Reduce dose or extend interval in renal impairment. Monitor thyroid function. Cats: more sensitive.
For people handling this medication
Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children. If accidental ingestion occurs, contact Poison Control (1-800-222-1222). Potassium iodide — Wash hands thoroughly with soap and water after handling. after handling. Iodide effects on thyroid with prolonged exposure.
Overdose
Contact your veterinarian. SSKI overdose causes iodism: excessive salivation, nasal discharge, and GI signs.
Sski dosage forms
| Product | Strength | Form | Size | Type |
|---|---|---|---|---|
| SSKI 1GM/ML SOLUTION: POTASSIUM IODIDE | 1 GM/ML | Solution | 1 | Commercial |
Sources
This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual (merckvetmanual.com); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)