Strep I.n. (pinnacle In) Vaccination

Intranasal modified-live Streptococcus equi (strangles) vaccine for immunization of horses against strangles (S. equi subsp. equi). Intranasal modified-live Streptococcus equi subspecies equi vaccine (Pinnacle I.N.). Mechanism: attenuated live S. equi organisms administered intranasally → stimulate mucosal (secretory IgA) and systemic humoral immunity → protection against strangles via antibody-mediated opsonization of S. equi. Intranasal route mimics natural infection for superior mucosal immunity. Key information Equine strangles modified live intranasal vaccine. Store at refrigerator temperature. Reconstitute and use immediately. DO NOT give IM — risk of abscess or purpura hemorrhagica. Administer intranasally only. Do not vaccinate horses in contact with immunocompromised animals.

Intranasal: administer prescribed volume into one or both nostrils using the provided nasal applicator. Restrain horse safely. Do not inject IM. Store refrigerated (2–8°C); do not freeze. If a dose is missed Contact your veterinarian to reschedule the missed vaccination. Timing of boosters is important for proper immune response.

Mild transient nasal discharge/sneezing (intranasal — expected). Low-grade fever. Do NOT inject IM (abscess risk with live organisms). Rare adverse reactions.

For animals Intranasal live vaccine — do not inject IM (abscess risk). Monitor for adverse reactions. Not approved for use in food-producing animals. For people handling this medication Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children. If accidental ingestion occurs, contact Poison Control (1-800-222-1222). Live intranasal vaccine — administered by veterinary staff. Do not allow splash into human nose or eyes. Wash hands thoroughly with soap and water after handling.

Contact your veterinarian. Intranasal vaccine overdose may cause local nasal irritation and transient signs.