Strongid Paste: Pyrantel Pamoate

Pyrantel pamoate for intestinal nematodes (strongyles, roundworms, pinworms) in horses. Pyrantel pamoate equine paste anthelmintic. Mechanism: nicotinic acetylcholine receptor agonist → spastic (depolarizing) neuromuscular paralysis in nematodes → worm expulsion by gut peristalsis. Poorly absorbed — acts locally in GI tract. Active against luminal stages of large and small strongyles, ascarids (Parascaris), and pinworms. Key information Pyrantel pamoate — see pyrantel entry. Paste formulation for horses. Weight-based dosing. Safe in pregnancy.

Oral paste (horses): administer via dose syringe into the back of the mouth at the correct weight marking. Oral suspension (small animals): Shake well before each use. Administer orally. May be given with food to improve compliance and reduce GI upset. Administer with food to reduce GI adverse effects. Store at room temperature; protect from light. If a dose is missed Give the missed dose as soon as you remember. If the next dose is due within a few hours, skip the missed dose and resume the regular schedule. Never give a double dose.

GI: mild vomiting, diarrhea, colic (uncommon). Generally very well tolerated. CNS toxicity only at extreme overdose. No systemic absorption — local GI action only.

For animals Resistance monitoring recommended. Not effective against encysted small strongyle larvae. Safe in pregnant mares at labeled doses. For people handling this medication Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children. If accidental ingestion occurs, contact Poison Control (1-800-222-1222). Pyrantel anthelmintic — Wash hands thoroughly with soap and water after handling. after handling. Keep out of reach of children.

Contact your veterinarian. Pyrantel paste overdose causes GI signs. Contact vet for guidance.