Surpass
Call to order(859) 281-9511General Drug Information and Indications
Topical diclofenac sodium NSAID cream for localized joint and soft tissue inflammation in horses.
Topical NSAID cream (diclofenac sodium 1% liposomal formulation). Mechanism: liposomal encapsulation delivers diclofenac transdermally to subcutaneous and periarticular tissues → inhibits local COX-1 and COX-2 → reduced prostaglandin synthesis → localized anti-inflammatory effect with minimal systemic absorption. For horses — direct application over inflamed joints or soft tissue.
Key information
Diclofenac sodium topical gel for horses. See diclofenac entry. Apply with gloves — human skin absorption. For horses only.
How to Give this Medication
Topical cream: wear gloves throughout application. Apply measured amount (dose ring/plunger) to clipped/clean skin directly over target joint or soft tissue. Rub in gently. Apply once or twice daily as directed. Wash hands after glove removal. Store at room temperature; protect from light.
If a dose is missed
Apply the missed dose as soon as you remember. If it is almost time for the next application, skip it and resume the normal schedule. Do not apply extra product to compensate.
Side Effects
Local: hair loss, scaling, contact dermatitis at application site (with prolonged use). Stinging if applied to broken skin. Systemic NSAID effects (low incidence due to limited absorption): GI, renal effects. Avoid applying to inflamed, abraded, or broken skin. Wash hands after application.
Precautions
For animals
Do not use concurrently with other NSAIDs or corticosteroids. Apply to target area only — avoid large-area application (systemic NSAID absorption). Monitor for GI ulceration; use with caution in animals with GI disease. Monitor renal function, hydration status, and urine output. Use minimum effective dose and frequency. Not approved for use in food-producing animals.
For people handling this medication
Wear gloves when handling. Wash hands thoroughly with soap and water after handling. Topical NSAID — wear gloves when applying. NSAID can be absorbed through the handler's skin causing GI and cardiovascular effects. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children. Pregnant women and women of childbearing age should avoid contact.
Overdose
Wash the area with soap and water if excessive product was applied. Contact your veterinarian if GI signs develop.
Surpass dosage forms
| Product | Strength | Form | Size | Type |
|---|---|---|---|---|
| SURPASS 124GM 1 % CREAM | 124 GM | Cream | 1 | Commercial |
Sources
This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual – Nonsteroidal Anti-inflammatory Drugs in Animals (https://www.merckvetmanual.com/pharmacology/inflammation/nonsteroidal-anti-inflammatory-drugs-in-animals); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)