Terramycin/polymixin B Oph Oint

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General Drug Information and Indications

Oxytetracycline/polymyxin B ophthalmic ointment for bacterial conjunctivitis and corneal infections. Oxytetracycline + polymyxin B ophthalmic ointment. Mechanism: oxytetracycline (bacteriostatic tetracycline — 30S ribosomal binding); polymyxin B (polypeptide membrane disruptor — bactericidal against gram-negatives). Combination covers broad spectrum of ocular bacterial pathogens. Key information Oxytetracycline ophthalmic ointment or oral/injectable. Ophthalmic: apply as directed; for ophthalmic use only. Injectable: deep IM; refrigerate; withdrawal times for food animals.

How to Give this Medication

Ophthalmic ointment: Instill into the conjunctival sac; avoid touching dropper tip to eye or periocular tissue. Apply 1 cm ribbon 2–4 times daily. Warm tube in hands before use. Otic: Clean ear canal before instillation. Gently massage base of ear after application to distribute medication. Verify TM integrity. Store at room temperature; protect from light. If a dose is missed This medication is administered by a veterinarian or veterinary staff in a clinical setting. Missed doses are managed by your veterinary team — contact your veterinarian to reschedule.

Side Effects

Ophthalmic: mild transient stinging/burning. Polymyxin B: ototoxicity if near ruptured TM. Neomycin: contact hypersensitivity. Generally well tolerated for topical ophthalmic use.

Precautions

For animals Verify tympanic membrane integrity before otic use (polymyxin B component). Use with caution in pregnant animals. Avoid in young animals (bone/tooth discoloration). For people handling this medication Wear gloves when handling. Wash hands thoroughly with soap and water after handling. Oxytetracycline ophthalmic — Keep out of reach of children. Pregnant women and women of childbearing age should avoid contact. Avoid human eye contact. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention.

Overdose

Contact your veterinarian. Oxytetracycline overdose causes GI and potentially kidney signs.

Terramycin/polymixin B Oph Oint dosage forms

ProductStrengthFormSizeType
TERRAMYCIN/POLYMIXIN B OPH OINT—Ointment1Commercial

Sources

This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual (merckvetmanual.com); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)