Thermazine

Silver sulfadiazine cream for treatment of burns and infected wounds; broad-spectrum antimicrobial. Silver sulfadiazine 1% topical cream. Mechanism: silver ions interfere with bacterial DNA replication and cell membrane function; sulfadiazine inhibits folate synthesis. Together provide broad-spectrum antimicrobial coverage for burns and chronic wounds. Creates moist environment supporting wound healing. Key information Silver sulfadiazine topical antimicrobial. For external wound use only. Do not use on large areas in cats.

Topical cream: apply to wound surface using gloved hands or sterile applicator. Cover with non-adherent dressing. Change daily. Store at room temperature; protect from light. If a dose is missed Apply the missed dose as soon as you remember. If it is almost time for the next application, skip it and resume the normal schedule. Do not apply extra product to compensate.

See silver sulfadiazine. Transient leukopenia with large-area application. Local burning. Sulfonamide hypersensitivity (rare). Argyria with prolonged large-area use (very rare).

For animals See silver sulfadiazine. Sulfonamide — avoid in sulfonamide-hypersensitive animals. Monitor WBC with large-area use. For people handling this medication Wear gloves when handling. Wash hands thoroughly with soap and water after handling. Silver sulfadiazine — wear gloves. Sulfonamide allergy risk. Keep out of reach of children. Pregnant women and women of childbearing age should avoid contact.

If excessive product was applied, wash the area thoroughly with mild soap and water. Contact your veterinarian if the animal shows any signs of irritation, lethargy, tremors, or other unusual behavior. Contact your veterinarian. Silver sulfadiazine on large areas may cause systemic effects.