Thyro-L
General Drug Information and Indications
Levothyroxine sodium powder for hypothyroidism in horses and dogs; thyroid hormone replacement.
Powdered levothyroxine sodium (L-thyroxine). Mechanism: T4 is converted peripherally to active T3 by deiodinases → T3 binds nuclear thyroid hormone receptors → gene transcription regulation → controls basal metabolic rate, cardiac function, GI motility, skin/hair quality, and mentation. For hypothyroidism in horses and dogs. Dose-sensitive — must titrate to effect.
Key information
Levothyroxine powder — for equine hypothyroidism/weight management. Store dry. Mix with feed. Monitor thyroid levels after 4–8 weeks.
How to Give this Medication
Oral powder (horses): mix accurately measured dose into a small portion of grain or carrier feed daily. Use a dedicated measuring spoon. Administer at consistent times. Store at room temperature; protect from light.
If a dose is missed
Administer as soon as you remember. If it is almost time for the next scheduled dose, skip the missed dose and resume the normal schedule. Never double up doses to make up for a missed one. A single missed dose is unlikely to cause immediate clinical problems.
Side Effects
Thyrotoxicosis (overdose): tachycardia, panting, weight loss, polydipsia, anxiety, diarrhea, hypertension. Cardiac arrhythmias. Clinical signs resolve with dose reduction. Monitor T4 levels.
Precautions
For animals
Monitor T4 levels and clinical signs. Avoid inhalation of powder during preparation. See levothyroxine precautions.
For people handling this medication
Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children. If accidental ingestion occurs, contact Poison Control (1-800-222-1222). Thyroid hormone powder — Wash hands thoroughly with soap and water after handling. after handling. Avoid inhaling dust. Keep out of reach of children.
Overdose
Contact your veterinarian. Levothyroxine overdose causes hyperthyroid-like signs.
Thyro-L dosage forms
| Product | Strength | Form | Size | Type |
|---|---|---|---|---|
| THYRO L 1 LB POWDER | — | Powder | 1 | Commercial |
| THYRO L 10 LB POWDER | — | Powder | 1 | Commercial |
Sources
This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual (merckvetmanual.com); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)