Timentin

Ticarcillin/clavulanate combination injectable for susceptible gram-negative and beta-lactamase-producing infections in horses. Extended-spectrum penicillin/beta-lactamase inhibitor combination (ticarcillin + clavulanate potassium). Mechanism: ticarcillin binds PBPs → inhibits cell wall synthesis; clavulanate irreversibly inhibits class A and C beta-lactamases → protects ticarcillin from enzymatic degradation → extended spectrum including beta-lactamase-producing Staph, E. coli, Klebsiella. Key information Ticarcillin/clavulanate IV. Extended-spectrum penicillin. Reconstitute; refrigerate; use within 24 hours (frozen 3 days). IV over 30 min. Penicillin allergy cross-reactivity possible.

IV: reconstitute and dilute in compatible IV fluid; infuse over 30 min. Use within 6 hrs of reconstitution at room temperature. Store refrigerated (2–8°C); do not freeze. (longer stability). If a dose is missed This medication is administered by a veterinarian or veterinary staff in a clinical setting. Missed doses are managed by your veterinary team — contact your veterinarian to reschedule.

Same as ticarcillin + clavulanate. Hypersensitivity. High sodium/potassium load. GI: diarrhea. Phlebitis (IV). Hypokalemia. Superinfection. Clavulanate increases GI adverse effects.

For animals See ticarcillin + clavulanate. Avoid in beta-lactam-hypersensitive animals. Reduce dose or extend interval in renal impairment. Monitor electrolytes. For people handling this medication Wear gloves when handling. Wash hands thoroughly with soap and water after handling. Beta-lactam/inhibitor combination — penicillin allergy risk. Wear gloves. Injectable — administered by veterinary staff only. Wash hands thoroughly with soap and water after handling. If accidentally self-injected, seek emergency medical attention immediately.

Contact your veterinarian. Ticarcillin/clavulanate overdose causes GI signs. IV administration — managed by veterinary staff.