Tri-hist Granules 20 Ounce

Antihistamine (pyrilamine maleate) for urticaria, pruritus, and respiratory allergic conditions in horses. Oral H1 antihistamine (pyrilamine maleate). First-generation antihistamine for horses. Mechanism: competitive H1 receptor antagonist → inhibits histamine-mediated increased vascular permeability, vasodilation, pruritus, and bronchospasm. Mild sedation via CNS H1 blockade. For allergic urticaria and respiratory allergy in horses. Key information Antihistamine/expectorant granule combination. Store at room temperature. For equine respiratory allergic conditions. Mix with feed.

Oral powder or tablets: Administer orally via dose syringe placed at the back of the tongue, or mix into a small amount of palatable feed. — mix into grain. Administer orally. May be given with food to improve compliance and reduce GI upset. Administer with food to reduce GI adverse effects. Administer 2–3 times daily. Store at room temperature; protect from light. If a dose is missed Administer as soon as you remember. If it is almost time for the next scheduled dose, skip the missed dose and resume the normal schedule. Never double up doses to make up for a missed one. Mix with feed.

CNS sedation (first-generation antihistamine). Anticholinergic effects: dry mouth, urinary retention, GI hypomotility. GI: vomiting (uncommon). Horses: agitation/excitability reported with some antihistamines — monitor.

For animals Use with caution in patients with glaucoma or urinary obstruction. Horses: monitor for agitation (paradoxical CNS effect with some antihistamines). For people handling this medication Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children. If accidental ingestion occurs, contact Poison Control (1-800-222-1222). Antihistamine — may cause drowsiness if accidentally ingested. Keep out of reach of children.

Contact your veterinarian. Antihistamine/expectorant overdose causes sedation and GI signs.