Tylosin Soluble Powder

Macrolide for Campylobacter-associated diarrhea and chronic diarrhea in dogs; Mycoplasma infections in cattle and poultry. Macrolide antibiotic (tylosin tartrate). Mechanism: binds 50S ribosomal subunit (23S rRNA L4/L22 proteins) → inhibits bacterial translocation and protein synthesis. Excellent activity against Mycoplasma and Campylobacter. Immunomodulatory effects on intestinal immune function. Soluble powder for water medication in poultry. IM injectable for dogs. Key information Macrolide antibiotic — primarily for GI bacterial overgrowth (Tylosin-responsive diarrhea in dogs). Store at room temperature. May be added to food. Long-term use generally well-tolerated. Not for horses (dysbiosis risk).

Oral powder (dogs): mix into food at appropriate dose. Administer with food to reduce GI adverse effects. Injectable: administer IM — deep IM injection only; do not give IV. Drinking water medication (poultry/swine): dissolve in drinking water per label. Store at room temperature; protect from light. If a dose is missed Administer as soon as you remember. If it is almost time for the next scheduled dose, skip the missed dose and resume the normal schedule. Never double up doses to make up for a missed one. Administer with food. Complete the full course.

GI: diarrhea, anorexia (most common). Pain/swelling at IM injection site. Cardiovascular: hypotension with rapid IV injection. Tympanic membrane reactions if used in ear with ruptured TM. Cardiotoxicity at overdose. Generally well tolerated at labeled doses.

For animals Observe food animal withdrawal times for milk and meat. GI: diarrhea common at high oral doses. Not for use in horses (significant GI adverse effects). Use with caution in pregnant animals. For people handling this medication Wear gloves when handling. Wash hands thoroughly with soap and water after handling. Macrolide antibiotic — wear gloves when handling (contact sensitization reported in humans). Keep out of reach of children. Pregnant women and women of childbearing age should avoid contact.

Contact your veterinarian. Overdose typically causes GI signs. Not for use in horses.