Ventipulmin

Clenbuterol hydrochloride (beta-2 agonist) for bronchodilation and management of recurrent airway obstruction (heaves/RAO) in horses; FDA-approved equine bronchodilator. Beta-2 adrenergic agonist bronchodilator (clenbuterol HCl). Mechanism: stimulates beta-2 receptors on bronchial smooth muscle → adenylyl cyclase activation → increased cAMP → smooth muscle relaxation and bronchodilation. More selective and longer-acting than albuterol. Also has anti-inflammatory effects on airway mucosa. FDA-approved for horses (oral syrup). Prohibited in racehorses (competition withdrawal times apply). Key information Clenbuterol — bronchodilator for horses. USEF prohibited substance — significant withdrawal time required. Store at room temperature. Dose titration required. Not for use in horses intended for human consumption.

Oral syrup: Administer orally via dose syringe placed at the back of the tongue, or mix into a small amount of palatable feed. via dose syringe or mixed into grain. Administer twice daily at consistent times. Wear gloves (prohibited substance residue). Store at room temperature; protect from light. If a dose is missed Give the missed dose as soon as you remember. If the next dose is due within a few hours, skip the missed dose and resume the regular schedule. Never give a double dose.

Cardiovascular: tachycardia, sweating, mild tremors (beta-2 sympathomimetic). Hypokalemia (beta-2 mediated K+ shift). Excitement/nervousness in some horses. Prohibited in competition horses (lengthy detection times in urine). GI: anorexia (transient with initiation).

For animals Prohibited in competition horses — extended urine detection time. Avoid in patients with cardiac arrhythmias, hyperthyroidism, or hypertension. Monitor heart rate. Drug interaction: beta-blockers antagonize effects. Not approved for use in food-producing animals. For people handling this medication Wear gloves when handling. Wash hands thoroughly with soap and water after handling. Beta-2 agonist — prohibited in competition horses. Wear gloves when handling syrup. Cardiovascular stimulant — avoid accidental ingestion. Keep out of reach of children.

Contact your veterinarian immediately. Clenbuterol overdose causes rapid heart rate, muscle tremors, sweating, and low potassium. Cardiac monitoring required.