Vetropolycin Oph Oint: Bacitracin-neomycin-polymixin

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General Drug Information and Indications

Bacitracin/neomycin/polymyxin B ophthalmic ointment for bacterial conjunctivitis and superficial ocular infections. Triple antibiotic ophthalmic ointment (bacitracin/neomycin/polymyxin B). Bacitracin: disrupts bacterial cell wall lipid carrier function → gram-positive bactericidal; neomycin: 30S ribosomal binding → protein synthesis inhibition; polymyxin B: membrane disruption → gram-negative bactericidal. Broad spectrum for bacterial ocular surface infections. Key information Bacitracin/neomycin/polymyxin B ophthalmic ointment. For ophthalmic/topical use. Do not use in corneal ulcer (polymyxin B cytotoxic). Store at room temperature.

How to Give this Medication

Ophthalmic ointment: Instill into the conjunctival sac; avoid touching dropper tip to eye or periocular tissue. Apply 1 cm ribbon to lower conjunctival sac. Apply 3–4 times daily. Warm tube in hands before use. Store at room temperature; protect from light. If a dose is missed Apply the missed dose as soon as you remember. If it is almost time for the next application, skip it and resume the normal schedule. Do not apply extra product to compensate.

Side Effects

Transient stinging upon instillation. Bacitracin component: rare hypersensitivity. Neomycin: contact allergy sensitization (one of most common topical allergens). Minimal systemic absorption.

Precautions

For animals Topical/otic — verify tympanic membrane integrity before otic use. Systemic oral use (GI decontamination): minimal absorption in normal GI tract but significant absorption in inflamed/damaged GI — nephrotoxicity risk. Contact allergy can develop with prolonged topical use. Not approved for use in food-producing animals. For people handling this medication Wear gloves when handling. Wash hands thoroughly with soap and water after handling. Triple antibiotic ophthalmic — neomycin allergy risk. Avoid human eye contact. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention.

Overdose

Contact your veterinarian. Ophthalmic antibiotic — systemic toxicity from topical use is very unlikely.

Vetropolycin Oph Oint: Bacitracin-neomycin-polymixin dosage forms

ProductStrengthFormSizeType
VETROPOLYCIN OPH OINT: BACITRACIN-NEOMYCIN-POLYMIXIN—Ointment—Commercial

Sources

This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual (merckvetmanual.com); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)