Viroptic

Trifluridine ophthalmic drops for herpetic keratitis in cats and horses; antiviral nucleoside analogue. Trifluridine ophthalmic solution 1% (trifluridine/trifluorothymidine). Mechanism: nucleoside analogue — competes with thymidine → incorporates into viral DNA → inhibits herpesvirus DNA replication. More potent topical antiviral than idoxuridine. Active against FHV-1 (cats) and EHV (horses). Frequent dosing required (q2h initially). Key information Trifluridine ophthalmic antiviral — see trifluridine entry. Refrigerate. Ophthalmic use only. Frequent dosing initially.

Ophthalmic solution: Instill into the conjunctival sac; avoid touching dropper tip to eye or periocular tissue. Instill 1 drop into affected eye(s) q2h (max 9 times/day) initially; reduce to q4h once re-epithelialization is evident. Store refrigerated (2–8°C); do not freeze. If a dose is missed Apply the missed dose as soon as you remember. If it is almost time for the next application, skip it and resume the normal schedule. Do not apply extra product to compensate.

Ophthalmic: transient burning, stinging. Superficial punctate keratopathy (corneal epithelial toxicity — frequency-dependent; limit to labeled schedule). Palpebral edema, chemosis. Corneal stromal edema (rare, prolonged use).

For animals Topical ophthalmic only. Frequent dosing required. Corneal epithelial toxicity with prolonged use — do not exceed labeled treatment duration. Used for FHV-1 in cats and EHV in horses. For people handling this medication Wash hands thoroughly with soap and water after handling. Antiviral ophthalmic — avoid human eye contact. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Wash hands thoroughly with soap and water after handling.

Contact your veterinarian. Trifluridine ophthalmic — systemic toxicity unlikely from eye drops.