General Drug Information and Indications

B-vitamin complex for treatment of deficiencies, metabolic stress, neurological support, and adjunct therapy during antibiotic use. Water-soluble B-vitamin complex. Mechanism: multiple B vitamins serve as enzyme cofactors — thiamine (B1): Krebs cycle; riboflavin (B2): FAD/FMN redox reactions; niacin (B3): NAD/NADH; B5: coenzyme A; pyridoxine (B6): amino acid/neurotransmitter metabolism; B12: DNA synthesis and myelin; folate: one-carbon transfers. Essential for energy metabolism, hematopoiesis, and neurological function. Key information Cyanocobalamin supplement. Store at room temperature; protect from light. IM or SQ injection. Safe supplement. Monitor for response.

How to Give this Medication

IV (B-complex injectable): administer slowly — anaphylaxis risk with rapid injection. IM: inject deep IM. Oral: mix into feed. Administer daily for acute deficiency; as needed for maintenance. Store at room temperature; protect from light. If a dose is missed Give the missed dose as soon as you remember. If you forget a day, simply resume the normal schedule the next day. Missing an occasional dose of this supplement is unlikely to cause harm.

Side Effects

Water-soluble — generally very safe; excess excreted in urine. Niacin (B3) at high doses: flushing, pruritis, GI upset. Pyridoxine (B6) excess: peripheral neuropathy (very high doses). IV injection: rare anaphylaxis (especially rapid B12 injection). Yellow urine (riboflavin — expected).

Precautions

For animals IV B12: administer slowly (anaphylaxis risk). Thiamine (B1): critical for PEM treatment in ruminants — administer immediately when PEM suspected. Generally safe at supplemental doses. For people handling this medication Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children. If accidental ingestion occurs, contact Poison Control (1-800-222-1222). B-vitamin complex — generally safe. Yellow urine discoloration (riboflavin — harmless). Wash hands thoroughly with soap and water after handling.

Overdose

Contact your veterinarian. B-vitamin overdose is rarely serious — excess water-soluble vitamins are excreted in urine. Very high doses may cause GI upset.

Vitamin B 12 dosage forms

ProductStrengthFormSizeType
VITAMIN B 12 1000 MCG/ML SOLUTION1000 MCG/MLSolution1Commercial

Sources

This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual (merckvetmanual.com); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)