General Drug Information and Indications

Antioxidant and collagen synthesis cofactor; supplementation for deficiency and oxidative stress; adjunct support in respiratory and immune conditions. Water-soluble antioxidant (ascorbic acid). Mechanism: free radical scavenger and electron donor; essential cofactor for collagen hydroxylase enzymes (prolyl and lysyl hydroxylase) → collagen synthesis and crosslinking; enhances iron absorption; supports immune cell (neutrophil, lymphocyte) function. Most species synthesize endogenously; supplementation indicated for deficiency or oxidative stress. Key information Ascorbic acid supplement/antioxidant. Store at room temperature; protect from light. Injectable: discard if discolored. High doses may cause GI upset. Generally safe.

How to Give this Medication

Oral: mix into feed or water. Administer with food to reduce GI adverse effects. IV (extra-label): dilute in compatible solution; infuse slowly. Store at room temperature; protect from light. If a dose is missed Give the missed dose as soon as you remember. If you forget a day, simply resume the normal schedule the next day. Missing an occasional dose of this supplement is unlikely to cause harm.

Side Effects

Generally very safe (water-soluble). High doses: GI upset, diarrhea (osmotic). Oxalate urolithiasis risk with very high chronic doses (cats — susceptible). Horses: generally safe at supplemental doses.

Precautions

For animals Dogs/cats synthesize vitamin C endogenously — routine supplementation rarely needed. Very high doses: GI upset, urolithiasis risk in cats (oxalate). Use in horses generally safe. For people handling this medication Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children. If accidental ingestion occurs, contact Poison Control (1-800-222-1222). Ascorbic acid — generally safe. High oral doses may cause GI upset in humans. Wash hands thoroughly with soap and water after handling.

Overdose

Contact your veterinarian. Vitamin C overdose causes GI signs (diarrhea) and, with chronic excess, kidney stone formation.

Vitamin C dosage forms

ProductStrengthFormSizeType
VITAMIN C 100 ML 250MG/ML INJECTABLE250 MG/MLInjectable1Commercial
VITAMIN C 250 MG/ML INJ SOLU250 MG/MLInjectable1Commercial
VITAMIN C 250ML 250MG/ML INJECTABLE: ASCORBIC ACID250 MG/MLInjectable1Commercial
VITAMIN C 5,000 IU PER ML INJECTABLE: ASCORBIC ACID 5,000 IU PER ML—Injectable1Commercial
VITAMIN C INJ - 250ML (VEDCO)—Injectable250MLCommercial
VITAMIN C INJ - 250ML (VETONE)—Injectable250MLCommercial

Sources

This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual (merckvetmanual.com); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)