Xxterra Herbal Paste

General Drug Information and Indications

Bloodroot-based zinc chloride herbal paste for treatment of equine sarcoids and cutaneous neoplasms; cytotoxic escharotic. Botanical escharotic paste (proprietary blend of sanguinarine/bloodroot alkaloids and zinc chloride). Mechanism: sanguinarine (benzophenanthridine alkaloid) induces tumor cell apoptosis via caspase activation; zinc chloride provides caustic escharotic effect causing local necrosis of abnormal tissue. Topical application to equine sarcoids induces tumor regression. Key information Bloodroot/zinc chloride herbal paste for equine sarcoids. For topical intralesional use only. CAUSTIC — wear gloves and eye protection. Causes significant tissue destruction. For veterinary use only.

How to Give this Medication

Topical escharotic (by trained professional): protect surrounding normal tissue with petroleum jelly. Apply thin layer of paste to sarcoid/papilloma surface using gloved applicator. Wear gloves at all times. Do not apply to mucous membranes or eyes. Apply per protocol (typically once or twice weekly). Dispose of applicators safely. Store at room temperature; protect from light. If a dose is missed This medication is administered by a veterinarian or veterinary staff in a clinical setting. Missed doses are managed by your veterinary team — contact your veterinarian to reschedule.

Side Effects

Local: severe inflammatory escharotic reaction (expected — caustic destruction of abnormal tissue). Excessive necrosis of surrounding normal tissue possible with over-application. Pain at application site. Systemic effects minimal with small-area topical use. Wear gloves — sanguinarine is toxic to handlers.

Precautions

For animals Apply ONLY to confirmed sarcoid/papilloma tissue — caustic to normal skin. Protect surrounding normal tissue with petroleum jelly. Monitor for depth of reaction. Do not use on mucous membranes or near eyes. Avoid in pregnant animals. For people handling this medication Wear gloves when handling. CAUSTIC ESCHAROTIC. Wear gloves at ALL times — sanguinarine is cytotoxic and caustic to normal human tissue. Keep out of reach of children. Pregnant women and women of childbearing age should avoid contact. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Avoid all contact with normal skin, eyes, and mucous membranes. If skin contact occurs, wash immediately. Keep out of reach of children.

Overdose

Contact your veterinarian. Caustic paste — excessive use causes severe tissue damage. For intralesional use only by veterinary professionals.

Xxterra Herbal Paste dosage forms

ProductStrengthFormSizeType
XXTERRA HERBAL PASTE - 1 OZ—Paste1Commercial

Sources

This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual (merckvetmanual.com); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)