Zeniquin
General Drug Information and Indications
Marbofloxacin fluoroquinolone for susceptible bacterial skin, urinary, and respiratory infections in dogs and cats.
Veterinary fluoroquinolone antibiotic (marbofloxacin). Mechanism: inhibits bacterial DNA gyrase and topoisomerase IV → bactericidal DNA replication inhibition. Concentration-dependent; post-antibiotic effect. Developed specifically for veterinary use in dogs and cats. Renally excreted.
Key information
Marbofloxacin — see marbofloxacin entry. Fluoroquinolone. Do not use in growing animals.
How to Give this Medication
Oral tablets: Administer orally. May be given with food to improve compliance and reduce GI upset. Administer with food to reduce GI adverse effects. Administer once daily. Store at room temperature; protect from light.
If a dose is missed
Administer as soon as you remember. If it is almost time for the next scheduled dose, skip the missed dose and resume the normal schedule. Never double up doses to make up for a missed one. Complete the full antibiotic course.
Side Effects
GI: vomiting, diarrhea, anorexia. Cartilage damage in growing animals. CNS: seizures (rare). Photosensitivity. Generally well tolerated in adult dogs and cats.
Precautions
For animals
See marbofloxacin. Avoid in growing animals. Reduce dose or extend interval in renal impairment. Not approved for use in food-producing animals.
For people handling this medication
Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children. If accidental ingestion occurs, contact Poison Control (1-800-222-1222). Fluoroquinolone — Wash hands thoroughly with soap and water after handling. after handling. Keep out of reach of children. Pregnant women and women of childbearing age should avoid contact.
Overdose
Contact your veterinarian. Marbofloxacin overdose causes GI and possible neurological signs.
Zeniquin dosage forms
| Product | Strength | Form | Size | Type |
|---|---|---|---|---|
| ZENIQUIN 200MG TABLET | 200 MG | Tablet | — | Commercial |
| ZENIQUIN 25MG TABLET: MARBOFLOXACIN | 25 MG | Tablet | 1 | Commercial |
Sources
This information is provided for educational purposes and is not a substitute for advice from your veterinarian. Source: Merck Veterinary Manual (merckvetmanual.com); Plumb's Veterinary Drug Handbook (Plumb, D.C., app.plumbs.com)