Zimecterin

Ivermectin paste for broad-spectrum parasite control in horses; strongyles, ascarids, pinworms, bots, and external parasites. Ivermectin 1.87% equine oral paste. Mechanism: macrocyclic lactone potentiates GluCl channels in parasites → hyperpolarization → paralysis and death. Active against 43 species and stages of equine parasites including large strongyles, small strongyles, ascarids, pinworms, bots (Gasterophilus), neck threadworms, and skin parasites. Key information Ivermectin equine paste. See ivermectin entry. Weight-based dosing. Safe in horses 4 months and older.

Oral paste (horses): administer via dose syringe into the back of the mouth at the correct weight marking. Turn plunger lock before use. Depress plunger completely. Store at room temperature; protect from light. If a dose is missed Give the missed dose as soon as you remember. If the next dose is due within a few hours, skip the missed dose and resume the regular schedule. Never give a double dose.

CNS toxicity in MDR1-mutant dogs if exposed to treated manure/bedding. Horses: generally very safe at labeled doses. Injection site reactions (if injectable form). GI: mild transient effects. Pain at Botfly die-off sites (larvicidal reaction).

For animals MDR1-mutant dogs exposed to treated manure/bedding: CNS toxicity risk. Not approved for use in food-producing animals. (horses intended for human consumption). Safe at labeled equine doses. For people handling this medication Wash hands thoroughly with soap and water after handling. Avoid contact with eyes; if contact occurs, flush with water for 15 minutes and seek medical attention. Keep out of reach of children. If accidental ingestion occurs, contact Poison Control (1-800-222-1222). Ivermectin paste — Wash hands thoroughly with soap and water after handling. after handling. Keep out of reach of children and away from dogs with MDR1 mutation.

Contact your veterinarian. Ivermectin overdose in horses causes neurological signs (tremors, ataxia, mydriasis). Supportive care required.